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Mass spectra of the samples were acquired in a Bio-Rad PCS mass spectrometer at low, medium, and high-power laser energies , , and nJ respectively. Cellular and molecular mechanisms of fibrosis. This could explain the seemingly contradictory reports of simultaneous collagen deposition and increased degradation within the same pelvic tissue. Differences in mRNA and protein expression of small proteoglycans in vaginal wall tissue from women with and without stress urinary incontinence. Review of proteomics with applications to genetic epidemiology. Therefore, thistechnology could help obviate the need for larger pelvic tissue samples in future studies. Differential protein profiling by SELDI-TOF MS is a powerful and reliable tool for urogynecological research since it allows us to study an array of proteins simultaneously using small tissue samples. Molecular and cellular biology.

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